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If you take REMERON, you should not take any other medicines that contain mirtazapine including REMERONSolTabВ®. A chemically similar drug in this class also produced optic nerve degeneration (Wallerian degeneration of retinogeniculate fibers) in clinically normal dogs in a dose-dependent fashion starting at 60В mg/kg/day, a dose that produced mean plasma drug levels about 30 times higher than the mean plasma drug level in humans taking the highest recommended dose (as measured by total enzyme inhibitory activity). Diltiazem plasma levels were not significantly affected by lovastatin or pravastatin. Children and infants—2 to 4 mg per kilogram (kg) (1 to 2 mg per pound) of body weight twice a day. Stinging, swelling, irritation, or redness of the treated skin may occur. Amy Allina, deputy director of the National Women’s Health Network, said most hormonal contraceptives are “extraordinarily safe,” so it’s imperative that women are well informed about all the options available to them.