Sometimes loss of vision can occur almost immediately. Osteoporosis is characterized by low bone mass that leads to an increased risk of fracture. The risk or severity of adverse effects can be increased when Carbamazepine is combined with Vigabatrin. Coronary artery disease or angina pectoris. Using progestins with estrogens may increase your chance of getting dementia, based on a study of women age 65 and older. Doses may be increased every 2 weeks according to clinical response, serum drug levels, and toxicity.