CAS• Article• Google Scholar• 23. I’m at 179 and am only 9lbs away from finally being able to get a breast reduction. Take tamoxifen exactly as directed. Prothrombin times should be closely monitored in patients already receiving coumarin anticoagulants who are started on Bicalutamide and adjustment of the anticoagulant dose may be necessary. Affecting primarily pre- pubertal children between 6 and 10 years, it is more common in males than females; rarely does the disease persist past age sixteen. Propranolol may increase the hypotensive activities of Deserpidine.