Both mechanisms amount to killing the bacterium. The pharmacokinetics of tolterodine immediate release and the 5-hydroxymethyl metabolite are not influenced by gender. Bloomington and Indianapolis: Indiana University Press. This may be more common after just starting this drug. Unlike Viagra, which is taken on an as-needed basis, flibanserin is to be taken every evening. Azaperone may increase the central nervous system depressant (CNS depressant) activities of Azelastine.