General Function Very long-chain fatty acid-coa ligase activity Specific Function Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. How long should you take Venlor XR? Voren, and other NSAIDs, have caused serious gastrointestinal toxicity, such as bleeding, ulceration, and perforation of the stomach, small intestine or large intestine. Lopid (gemfibrozil) with all of your drugs and health problems. Asian Pacific Journal of Tropical Disease. It occurs when your pores, or hair follicles, get clogged with oil and dead skin cells and create a place for bacteria to grow and thrive.