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The serum concentration of Androstenedione can be increased when it is combined with Ethinyl Estradiol. Such decrease, possibly due to interference with B12 absorption from the B12-intrinsic factor complex, is, however, very rarely associated with anemia and appears to be rapidly reversible with discontinuation of GLUCOPHAGE or vitamin B12 supplementation. LABA, such as salmeterol, the active ingredient in SEREVENT DISKUS, increase the risk of asthma-related death [see Warnings and Precautions (5. Se o medicamento for administrado a pacientes demasiadamente ativos ou agitados, pode ocorrer aumento de ansiedade e de agitação. Foye’s principles of medicinal chemistry. Ketotifen, sold under the brand name Zaditor among others, is a first-generation noncompetitive H 1- antihistamine and mast cell stabilizer.